U.S. Delegation "Life Sciences Exchange Project" Conference Center of Magnetic Resonance (CERM) - Università degli Studi di Firenze, May 12, 2006 NeuroLife Noninvasive Solutions Daniel D. McChesney, MD, MBA NeuroLife Noninvasive Solutions is developing a noninvasive device to accurately monitor brain pressure. The company, which is led by two physicians Ernest Braxton and Daniel McChesney, is focused on development of a tool that measures intracranial pressure, allowing medical professionals to better diagnose and treat head injured patients at risk for brain damage and death. “Unlike many other noninvasive medical tests, brain pressure is still measured invasively by boring a hole through the skull and inserting a catheter into the brain, placing head injured patients at risk for brain infections and brain damage.” said Daniel McChesney M.D., President and Chief Executive Officer of NeuroLife. “To know this is to understand the advantages and promise of NeuroLife’s noninvasive iSCAN technology. The iSCAN device detects elevated brain pressure through the eye using a camera, fiber optics and proprietary software to measure changes in the eye’s blood supply.” iSCAN’s measurement of the eye’s blood supply uses a technique similar to that used by eye doctors to measure the blood pressure of the eye by pressing gently against the eye until the retinal artery collapses temporarily. Because of the close relationship between the eye and the brain, small changes in the eye’s blood supply often correlate with brain pressure. “Through the use of this noninvasive technology, we reduce the risks of possible infection, brain damage, and bleeding associated with invasive procedures,” said Dr. Braxton, NeuroLife’s Chief Scientific Officer. “The mortality and disability rate associated with the measurement of brain pressure will likely improve with the application of the iSCAN.” The company is currently in the prototype phase, and will move into FDA trials in 2007.
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